Tuesday, 4 June 2019

Miracle Medicinal Neem Tree

Azadirachta indica, commonly known as neem, has attracted worldwide prominence in recent years, owing to its wide range of medicinal properties.

Neem has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a cynosure of modern medicine. Neem elaborates a vast array of biologically active compounds that are chemically diverse and structurally complex.

More than 140 compounds have been isolated from different parts of neem. All parts of the neem tree- leaves, flowers, seeds, fruits, roots and bark have been used traditionally for the treatment of inflammation, infections, fever, skin diseases and dental disorders.

The medicinal utilities have been described especially for neem leaf. Neem leaf and its constituents have been demonstrated to exhibit immunomodulatory, anti-inflammatory, antihyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, antioxidant, antimutagenic and anticarcinogenic properties.

This review summarises the wide range of pharmacological activities of neem leaf.

Many people have never heard of it, but could an evergreen tree from India offer powerful health benefits… including the ability to fight cancer?

The Neem Tree whose biological name is Azadirachta indica also known as Indian Lilac is an evergreen tree that belongs to the mahogany family. While neem is often used to make furniture, this tree also offers powerful anti-cancer and healing benefits.

Neem grows freely in the tropical and semi-tropical regions of India and the Indian subcontinent, including Nepal, Pakistan, Bangladesh, and Sri Lanka. A. indica can also be found growing in Africa, the Americas, Australia, and the South Pacific islands. Its fruits and seeds are the source of medicinal neem oil.

In the ancient Indian language Sanskrit, the neem tree is called “Aristha” or “reliever of sicknesses.” In the Vedas (a large body of texts originating in ancient India, which make up the oldest known scriptures of Hinduism), neem is known as “Sarva Roga Nivarini” meaning “One that cures all ailments and ills.”

Neem is referred to as the “Miracle Tree” and because of its tremendous medical properties, the neem tree is also considered to be a “village pharmacy” in India. Extracts of neem leaves, twigs, bark, seeds, and flowers are integral components of many traditional remedies in the Indian medical system of Ayurveda.

These remedies date back, by some accounts, nearly 5,000 years.

More than 60 different biologically active neem tree compounds have been identified and used for a wide variety of health and medical applications. Some of these include nimbin, nimbolide, azadirachtin A, nimbidiol, quercetin, and nimbidin.

Neem leaves are dried in India and placed in cupboards to prevent insects eating the clothes, and also in tins where rice is stored. These flowers are also used in many Indian festivals like Ugadi.

A vegetable

The tender shoots and flowers of the neem tree are eaten as a vegetable in India. A souplike dish called Veppampoo charu (Tamil) made of the flower of neem is prepared in Tamil Nadu. In Bengal, young neem leaves are fried in oil with tiny pieces of eggplant (brinjal).

The dish is called neem begun bhaja and is the first item during a Bengali meal that acts as an appetizer. It is eaten with rice.

Neem is used in parts of mainland Southeast Asia, particularly in Cambodia, Laos where it is called kadao, Thailand where it is known as sadao or sdao, Myanmar where it is known as tamar and Vietnam where it is known as sầu đâu and is used to cook the salad gỏi sầu đâu.

Even if lightly cooked, the flavour is quite bitter and the food is not enjoyed by all inhabitants of these nations, though it is believed to be good for one's health.

Neem gum is a rich source of protein. In Myanmar, young neem leaves and flower buds are boiled with tamarind fruit to soften its bitterness and eaten as a vegetable. Pickled neem leaves are also eaten with tomato and fish paste sauce in Myanmar.

Traditional medicinal

Products made from neem trees have been used in India for over two millennia for their medicinal properties. Neem products are believed by Siddha and Ayurvedic practitioners to be anthelmintic, antifungal, antidiabetic, antibacterial, antiviral, contraceptive, and sedative.

It is considered a major component in siddha medicine and Ayurvedic and Unani medicine and is particularly prescribed for skin diseases. Neem oil is also used for healthy hair, to improve liver function, detoxify the blood, and balance blood sugar levels.

Neem leaves have also been used to treat skin diseases like eczema, psoriasis, etc.

Insufficient research has been done to assess the purported benefits of neem, however. In adults, short-term use of neem is safe, while long-term use may harm the kidneys or liver; in small children, neem oil is toxic and can lead to death.

Neem may also cause miscarriages, infertility, and low blood sugar.

Neem oil can cause some forms of toxic encephalopathy and ophthalmopathy if consumed in large quantities.

Neem is a key ingredient in non-pesticidal management (NPM), providing a natural alternative to synthetic pesticides. Neem seeds are ground into powder that is soaked overnight in water and sprayed onto the crop. To be effective, it must be applied repeatedly, at least every ten days.

Neem does not directly kill insects on the crop. It acts as an anti-feedant, repellent, and egg-laying deterrent and thus protect the crop from damage.

The insects starve and die within a few days. Neem also suppresses the hatching of pest insects from their eggs. Neem-based fertilizeres have been effective against the pest southern armyworm. Neem cake is often sold as a fertilizer.

Neem oil has been shown to avert termite attack as an ecofriendly and economical agent.

Applications of neem oil in the preparation of polymeric resins have been documented in the recent reports. The synthesis of various alkyd resins from neem oil is reported using a monoglyceride (MG) route and their utilization for the preparation of PU coatings.

The alkyds are prepared from reaction of conventional divalent acid materials like phthalic and maleic anhydrides with MG of neem oil.

The juice of this plant is a potent ingredient for a mixture of wall plaster, according to the Samarangaṇa Sutradhara, which is a Sanskrit treatise dealing with Silpasastra or Hindu science of art and construction.

- Cleaning teeth by chewing stick

- Hair Comb, Wood of neem tree is used to handcraft hair combs and it is believed that regular use can control hair loss, dandruff and other scalp problems.

- Toiletries: Neem oil is used for preparing cosmetics such as soap, shampoo, balms, and creams as well as toothpaste

- Animal Treatment: Used to treat sweet itch and mud fever in horses

- Toothbrush: Traditionally, slender neem twigs called datun are first chewed as a toothbrush and then split as a tongue cleaner. This practice has been in use in India, Africa, and the Middle East for centuries.

It is still used in India's rural areas. Neem twigs are still collected and sold in rural markets for this use. It has been found to be as effective as a toothbrush in reducing plaque and gingival inflammation.

- Tree: Besides its use in traditional Indian medicine, the neem tree is of great importance for its anti-desertification properties and possibly as a good carbon dioxide sink.

- Neem gum is used as a bulking agent and for the preparation of special purpose foods.
Neem blossoms are used in Andhra Pradesh, Tamil Nadu, and Karnataka to prepare Ugadi pachhadi. A mixture of neem flowers and jaggery or unrefined brown sugar is prepared and offered to friends and relatives, symbolic of sweet and bitter events in the upcoming new year, Ugadi.
Bevina hoovina gojju a type of curry prepared with neem blossoms is common in Karnataka throughout the year. Dried blossoms are used when fresh blossoms are not available. In Tamil Nadu, a rasam or veppam poo rasam made with neem blossoms is a culinary speciality.

- Cosmetics: Neem is perceived in India as a beauty aid. Powdered leaves are a major component of at least one widely used facial cream. Purified neem oil is also used in nail polish and other cosmetics.

- Bird repellent: Neem leaf boiled in water can be used as a very cost-effective bird repellent, especially for sparrows.

- Lubricant: Neem oil is non-drying and it resists degradation better than most vegetable oils. In rural India, it is commonly used to grease cart wheels.

- Fertilizer: Neem extract is added to fertilizers urea as a nitrification inhibitor.

- Plant protectant: In Karnataka, people grow the tree mainly for its green leaves and twigs, which they puddle into flooded rice fields before the rice seedlings are transplanted.

- Resin: An exudate can be tapped from the trunk by wounding the bark. This high protein material is not a substitute for polysaccharide gum, such as gum arabic. It may, however, have a potential as a food additive, and it is widely used in South Asia as Neem glue.

- Bark: Neem bark contains 14% tannin, an amount similar to that in conventional tannin-yielding trees such as Acacia decurrens. Moreover, it yields a strong, coarse fibre commonly woven into ropes in the villages of India.

- Honey: In parts of Asia neem honey commands premium prices, and people promote apiculture by planting neem trees.

- Soap: 80% of India's supply of neem oil now is used by neem oil soap manufacturers. Although much of it goes to small-scale speciality soaps, often using cold-pressed oil, large-scale producers also use it, mainly because it is cheap.

Additionally it is antibacterial and antifungal, soothing, and moisturising. It can be made with up to 40% neem oil. Generally, the crude oil is used to produce coarse laundry soaps.

- Animal feed: Neem leaves can be occasionally used as forage for ruminants and rabbits.

Neem leaf or bark is considered an effective pitta pacifier because of its bitter taste. Hence, it is traditionally recommended during early summer in Ayurveda that is, the month of Chaitra as per the Hindu Calendar which usually falls in the month of March – April.

In the Indian states of Andhra Pradesh, Karnataka and Telangana, Neem flowers are very popular for their use in 'Ugadi Pachhadi' soup-like pickle, which is made on Ugadi day.

In Andhra Pradesh, Karnataka, and Telangana, a small amount of Neem and Jaggery (Bevu-Bella) is consumed on Ugadi day, the Telugu and Kannada new year, indicating that one should take both bitter and sweet things in life, joy and sorrow.

During Gudi Padva, which is the New Year in the state of Maharashtra, the ancient practice of drinking a small quantity of neem juice or paste on that day, before starting festivities, is found.

As in many Hindu festivals and their association with some food to avoid negative side-effects of the season or change of seasons, neem juice is associated with Gudi Padva to remind people to use it during that particular month or season to pacify summer pitta.

In Tamil Nadu during the summer months of April to June, the Mariamman temple festival is a thousand-year-old tradition. The Neem leaves and flowers are the most important part of the Mariamman festival.

The statue of the goddess Mariamman will be garlanded with Neem leaves and flowers. During most occasions of celebrations and weddings the people of Tamil Nadu adorn their surroundings with the Neem leaves and flowers as a form of decoration and also to ward off evil spirits and infections.

The Tamil people traditionally consider that the various diseases of pox and measles are caused directly by the deity Mariamman herself and use the Neem leaves alone to relieve from infection.

In the eastern coastal state of Odisha the famous Jagannath temple deities are made up of Neem heart wood along with some other essential oils and powders.

Ayurveda was the first to bring the anthelmintic, antifungal, antibacterial, and antiviral constituents of the neem tree to the attention of natural products chemists. The process of extracting neem oil involves extracting the water-insoluble components with ether, petrol ether, ethyl acetate, and dilute alcohol.

The provisional naming was nimbin (sulphur-free crystalline product with melting point at 205 °C, empirical composition C7H10O2), nimbinin with similar principle, melting at 192 °C, and nimbidin cream-coloured containing amorphous sulphur, melting at 90–100 °C.

Siddiqui identified nimbidin as the main active antibacterial ingredient, and the highest yielding bitter component in the neem oil. These compounds are stable and found in substantial quantities in the Neem. They also serve as natural insecticides.

Neem-coated urea is being used an alternate to plain urea fertilizer in India. It reduces pollution, improves fertilizer's efficacy and soil health.

According to Ayurveda, the neem tree offers numerous health benefits. Let’s take a look at the specific uses and health benefits offered by various parts of the neem tree.

Neem leaves are reputed to possess antibacterial, antiviral, anti-fungal, and anti-malarial properties – which is why their extracts are used to treat skin infections, acne, boils, burns, and many other skin problems.Some traditional uses for neem leaves include:

Skin cleanser – Neem stops the growth of the acne-causing bacteria P. acnes, along with suppressing P. acnes-induced inflammation.

Wound healer – a paste of neem leaves is applied on wounds, skin eruptions, and insect bites. When combined with turmeric, this paste is also used to treat skin itching, eczema, ring worm, and other mild skin diseases.

Hair conditioner – Neem leaf extracts and paste are used to condition the hair and scalp and are believed to strengthen hair and promote hair growth.

Anti-dandruff agent – water in which neem leaves have been boiled is applied to hair after regular shampooing to rid the scalp of dandruff.
Eye cleansing and soothing – extract of neem leaves in water is used to wash the eyes and is said to offer relief from irritation, tiredness, and redness.

Immune booster – consuming extracts of neem leaves and bark again, made by boiling in water are believed to increase overall immunity. These extracts also reputedly lower blood sugar levels and heal ulcers.

Unlike the rest of the neem tree which is bitter, the white and delicate neem flowers possess a sweet, almost jasmine-like scent. They are used fresh, dried, or in a powdered form as food and as garnish in some Indian cooking traditions.

Neem flowers are used medicinally to treat anorexia, nausea, and intestinal worms. They are also used in aromatherapy because of their calming effect.

Neem Twigs, before toothbrushes became common, people in India would traditionally chew away at neem twigs in the morning. In Indian villages, many people still do this.

This habit helps to fight germs, maintain alkaline levels in saliva, keep bacteria away, heal swollen gums, and leads to whiter teeth. Finally, the twig also shreds into bristle-like threads that help to remove and prevent plaque.

Neem oil extracted from fruits and seeds of the neem tree is rich in antioxidants and fatty acids. This makes it an ideal ingredient in cosmetics and beauty products such as soaps, hair oil, hand wash, and soap.

Traditional uses of Neem oil include:

Skin cleanser – 2-3 drops of neem oil diluted with water and applied on the skin helps to keep the skin clear, removing acne, blackheads, and helping to heal skin diseases.

Skin toner and mosquito repellent – Neem oil contains high levels of vitamin E and is very nourishing for the skin, helping to maintain a balanced tone. When added to face packs, it helps to tone aging skin and relieves irritation and itching. It is also an excellent mosquito repellent.

Natural shampoo – Rubbing neem oil into the scalp can strengthen hair, prevent hair fall, and remove dandruff.

Anti-Cancer Benefits of Neem, excitingly, naturally-occurring bioactive compounds obtained from various parts of the neem tree have been shown to induce “apoptosis” or programmed cell death in different types of tumor cells in laboratory conditions.

Some of these compounds stimulate the immune system to fight cancer cells better. Neem compounds may also prevent cancer development by generating high levels of antioxidants and carcinogen-detoxifying enzymes.

Overall, neem compounds show impressive anti-cancer potential against many human cancer cell lines and animal models for human cancers. Among these are colon, stomach, pancreas, lung, liver, skin, oral, prostate, and breast cancers.

Anti-Carcinogenic and Anti-Mutagenic Effects of Neem, over the last two decades, cancer researchers have convincingly shown that cancer formation as a result of exposure to certain specific mutagens and pro-carcinogens can be prevented by neem extracts.

As a result, these extracts and bioactive neem compounds may one day play a key role in the future development of chemopreventive anti-cancer agents.

Neem Stops Cancer Cell Growth and Migration, Researchers in India, Europe, and Japan have shown that bioactive compounds present in neem bark, leaves, and seed oil could be used to treat a wide variety of cancers.

For instance, a recently published study showed that nimbolide – a bioactive neem compound – was able to induce apoptosis in pancreatic cancer cells, to the extent that the size and number of cancer cell colonies was reduced by 80%.

Apoptosis or programmed cell death is a genetically driven process that happens naturally all the time in the body. It’s a safe way to get rid of diseased and dying cells without affecting nearby healthy cells and tissues.

Anti-cancer practitioners are also trying to eliminate cancer cells by inducing apoptosis selectively in them, without affecting normal cells. In this regard, neem is an excellent choice as neem extracts as well as purified neem compounds have been shown to cause apoptosis in cancer cells.

Nimbolide also reduced the ability of pancreatic cancer cells to migrate and invade other areas of the body by an astonishing 70%. Migration and invasion – known scientifically as “metastasis” – of cancer cells to other areas of the body is the main reason why pancreatic and other cancers are so lethal.

Pancreatic cancer is the most lethal of all, with 94% of patients dying within the first five years of diagnosis, with no conventional treatment in sight.

One of the most promising aspects of this study was that nimbolide did not harm healthy cells. In other words, using nimbolide to treat pancreatic and perhaps other forms of cancer in the near future may not result in the toxic side effects that chemotherapy and radiation typically do.

Neem Potentiates Anti-Cancer Drugs and Protects Against Their Toxicity, Neem preparations have been shown to potentiate or enhance the effect of the actions of anti-cancer agents. They also provide protection against the life-threatening side effects of some of these very toxic drugs.

For instance, Cisplatin and 5-fluorouracil (5-FU) are well-known anti-cancer drugs with devastating side effects, especially because they also massively kill normal blood cells. Normally, another drug known as granulocyte colony stimulating factor (GCSF) is given along with these two anti-cancer drugs to try and minimize their toxic side effects.

Interestingly, pretreatment with neem leaf preparation (NLP) has been found to protect blood cells in laboratory mice treated with Cisplatin and 5-FU.

This means NLP could potentially be a safer and cheaper substitute than granulocyte colony stimulating factor. GCSF is not only expensive, but is also known to promote angiogenesis and tumor development on its own!

Neem Enhances the Actions of Detoxifying Enzymes, extracts of neem leaves have been shown to enhance the actions of so-called “phase-II hepatic enzymes” such as Glutathione S-transferases and DT-diaphorase. Both these enzymes are known to be involved in detoxification of chemical carcinogens.

Additionally, neem leaf extracts enhance the activity of various liver antioxidant enzymes. Amongst these are glutathione reductase, glutathione peroxidase, and superoxide dismutase, which are known to help in detoxifying the body.

Neem: Bioimmunotherapy Against Cancer, boosting the body’s own immune system to target specific health risks is known as bioimmunotherapy. Anti-cancer practitioners have begun to incorporate this strategy to fight cancer. Recent studies show that neem may exert some of its anti-cancer effects by enhancing the body’s immune response.

Recently published peer-reviewed studies carried out at the Chittaranjan National Cancer Institute in Kolkata, India, showed that a bioactive protein from leaves of the neem tree prevents cancer cells from growing in mice by doing exactly this.

Instead of targeting the cancer cells directly, this protein – known as Neem Leaf Glycoprotein (NLGP) – acts on immune cells present within the tumor’s immediate surroundings, known as the “tumor microenvironment”.

Normally, immune cells attack and destroy cancer cells. However, as some tumors grow, immune cells in their microenvironment become “enslaved” by cancer cells. In a bizarre role-reversal, these immune cells now begin to promote the growth and proliferation of cancer cells in the tumor instead of fighting them.

In a dramatic twist straight out of a thriller, NLGP seemingly returns immune cells in the tumor microenvironment to a more normal state. It makes them hostile again to cancer cells and prevents them from growing any further.

A good example can be found in one group of cancer-killing immune cells known as the CD8+ or “killer” T cells. When triggered by NLGP, the number of these T cells was seen to rise significantly, helping to restrict cancer growth.

What’s more, these killer T cells also showed a greater cancer cell killing capacity when compared to killer T cells that were not treated with NLGP.

Various parts of the neem tree and its extracts have been used by humans for medicinal purposes for hundreds of years.While the uses of neem seem limitless, precautions need to be taken and neem products should be used with care. Indiscriminate consumption of higher than necessary doses may sometimes cause unpleasant side effects.

Some people are allergic to neem compounds – leading to itching, swelling of the mouth and throat, wheezing, and breathing difficulties. In very rare instances, some neem compounds may also damage the liver and kidneys.

Therefore, it is always advisable not to medicate yourself with any products containing neem extracts or neem compounds. Always consult a trustworthy alternative healthcare provider first, and be sure to apply or consume these products under properly qualified supervision.

The neem tree has been a source of safe and powerfully effective solutions for human health problems for many hundreds of years.

Over the past few decades, modern scientific researchers have purified some of the active ingredients from this ancient “reliever of sicknesses” – and they are gradually beginning to understand their healing mechanisms.

There is now compelling scientific evidence that many neem compounds possess promising anti-cancer properties. In the near future, combinations of bioactive neem compounds, either on their own or given along with anti-cancer drugs, chemotherapy, and radiotherapy seem likely to become a reliable standard treatment of choice for many cancer patients.

Live your life without the threat of cancer.

Tall, with dark-green pointy leaves, the neem tree of India is known as the "village pharmacy." As a child growing up in metropolitan New Delhi, Sonia Arora recalls on visits to rural areas seeing villagers using neem bark to clean their teeth. Arora's childhood memories have developed into a scientific fascination with natural products and their power to cure illnesses.

Now an assistant professor at Kean University in New Jersey, Arora is delving into understanding the curative properties of the neem tree in fighting the virus that causes AIDS.

She presented her data at a poster session on April 22, at the Experimental Biology 2012 meeting in San Diego. Her preliminary results seem to indicate that there are compounds in neem extracts that target a protein essential for HIV to replicate.

If further studies support her findings, Arora's work may give clinicians and drug developers a new HIV-AIDS therapy to pursue.

Extracts from neem leaves, bark and flowers are used throughout the Indian subcontinent to fight against pathogenic bacteria and fungi. "The farther you go into the villages of India, the more uses of neem you see," says Arora.

Tree branches are used instead of toothpaste and toothbrushes to keep teeth and gums healthy, and neem extracts are used to control the spread of malaria.

Practitioners of Ayurvedic medicine, a form of traditional Indian alternative medicine, even prescribe neem extracts, in combination with other herbs, to treat cardiovascular diseases and control diabetes. The neem tree, whose species name is Azadirachta indica and which belongs to the mahogany family, also grows in east Africa.

Arora's scientific training gave her expertise in the cellular biology of cancer, pharmacology, bioinformatics and structural biology. When she established her laboratory with a new research direction at Kean University in 2008, Arora decided to combine her knowledge with her long-time fascination with natural products. The neem tree beckoned.

Arora dived into the scientific literature to see what was known about neem extracts. During the course of her reading, Arora stumbled across two reports that showed that when HIV-AIDS patients in Nigeria and India were given neem extracts, the amount of HIV particles in their blood dropped.

Intrigued, Arora decided to see if she could figure out what was in the neem extract that seemed to fight off the virus.

She turned to bioinformatics and structural biology to see what insights could be gleaned from making computer models of HIV proteins with compounds known to be in neem extracts. From the literature, she and her students found 20 compounds present in various types of neem extracts.
When they modeled these compounds against the proteins critical for the HIV life-cycle, Arora and her team discovered that most of the neem compounds attacked the HIV protease, a protein essential for making new copies of the virus.

Arora's group is now working on test-tube experiments to see if the computer models hold up with actual samples. If her work bears out, Arora is hopeful that the neem tree will give a cheaper and more accessible way to fight the HIV-AIDS epidemic in developing countries, where current therapies are priced at levels out of reach of many people.
And, of course, she notes, there is the potential of discovering new drugs based on the molecules present in neem.

Neem Tree, also known as 'Azadirachta indica' is a tree native to India. In Sanskrit, neem is arista, which means something that is perfect, imperishable and complete. Not only its leaves, but the tree's seeds, roots and bark also contain important compounds that have many medicinal and beauty properties. The tree is supposed to denote 'good health' in our Ayurveda.

Neem is best known for its anti-aging properties. Due to its antioxidant properties, neem protects the skin from harmful UV rays, pollution and other environmental factors. The vitamins and fatty acids in neem improve and maintain the elasticity of the skin, reduce wrinkles and fine lines. This make you and your skin look rejuvenated and youthful.

Neem is also beneficial in fighting against fungal infection. Its anti-fungal and anti-bacterial properties keep the harmful bacteria and fungi at bay. Thus, it protects the skin and keeps the skin related diseases away.

Ayurveda, which follows the natural ways for treatment and medicine, has been using extracts of neem tree as a key ingredient, for good health and well being. Here are some of the herbal remedies, health benefits and magical properties of neem.

Neem Herbal Remedy and Benefit : One tree pharmacy
Not only in Ayurvedic medicines, neem tree extracts have been a part of many home remedies that Indians have been following since time immemorial. We use neem to treat hair and skin issues.

Neem Herbal Remedy and Benefit : Anti-fungal and anti-bacterial. Neem leaves are used to treat fungal and bacterial infections. They are used to treat warts as well as chicken pox. Either the paste is applied on the affected area or the person is made to bathe in neem water. It can also treat foot fungi.

You can keep neem soaked cotton near your windows or burn neem leaves to ward off insects. It is extremely effective and is used to fight mosquito menace.

Neem Herbal Remedy and Benefit,Increases immunity. Many Ayurveda experts recommend daily intake of neem capsules. Neem tea is also widely prescribed to reduce fever, especially the malaria one. Since neem tastes bitter, the tea acquires a similar taste but works magically.

Neem Herbal Remedy and Benefit. Nature's toothbrush Chewing neem twigs for dental hygiene and care is an age-old Indian tradition. In Indian households, people used to brush their teeth using twigs of neem. And these days you find neem-based toothpaste to ensure good dental health.

Due to its antibacterial, anti-inflammatory and antifungal properties, it keeps away all sorts of dental infections and diseases.

Neem Herbal Remedy and Benefit Strong and long hair. Neem also helps in strengthening hair quality and promotes growth of hair. Neem paste is also used as a hair conditioner. Due to its antibacterial, antifungal and anti-inflammatory properties, neem is an excellent way to curb dandruff.

This makes hair follicles stronger, thus encouraging hair growth too. It provides the required nourishment and conditioning to the roots, making them stronger and shinier.

Neem Herbal Remedy and Benefit Treat skin disorder. There are many formulations in Ayurveda that are used to treat skin issues. It is because it has a detoxifying property. It is used to treat sczema and other skin infections.

Neem can heal wounds without leaving any ugly scars. It also prevents septic infections. Neem is commonly used to heal wounds because of its antiseptic properties. Apply a little amount of neem oil onto the wounds and on scars, daily. Neem Oil contains the necessary fatty acids, which also promote wound healing and make your skin healthy.

Acne relief. Neem also has anti-inflammatory property that reduces acne. The neem oil is believed to relieve skin dryness, skin itchiness and redness. It also prevents pimples and skin blemishes.

Neem is also used in organic farming. The popular neem seed cake, which is basically a neem seed residue which is left after oil extraction, is extremely beneficial for enriching the soil. It also brings down nitrogen loss and works as a nematicide.

Neem is also an excellent source of moisturizer for the skin. By applying neem oil, the fatty acids and vitamins in it moisturize and condition your skin, making it clearer and youthful. The vitamin E in neem oil repairs the damaged skin and also limits the effect of environment changes that can lead to skin damage.

You will commonly find neem used in products such as bath powders, shampoos, skin lotion, toothpaste and many companies have even started marketing neem leaf capsule for better immunity.

With the dengue menace round the corner, it also works as a brilliant source to repel insects.

Medicinal uses of the tree of life – Neem Plant

Cardiac Problems: Infusions of leaves in HOT water when taken removes bad sugars and toxins from blood, dilates blood vessels, improves blood circulation and balances heart pumping rates.

High Blood Pressure: It relaxes erratic heart beats and balances blood pressure. Research shows that the intravenous administration of neem leaf alcohol extract significantly reduces blood pressure.

Eczema: Dried leaves are burnt on red hot charcoal and covered to cure eczema.

Pesticides/Insecticide: Pound a few handful of seeds, add water, mash and filter out solution with a clean sieve. Use to spray your crops.

Contraceptive: Neem is a natural contraceptive; it blocks spermatogenesis or production of sperm cells without affecting the production of testosterone. It is thus believed to be an ideal contraceptive for birth control as it is natural, available, nontoxic and affordable to almost all.

Neem Oil: It can be used as a spermicide. It’s applied deep in the vagina or intra-vaginally before sexual intercourse. It kills sperms and prevents pregnancy.

Cancers: Leaves are rich in antioxidants. They help prevent cancers and also used against developing cancers.

Digestion: Take teas of neem leaves or barks to treat digestive problems.

Typhoid & Malaria: Neem leaves tea is an effective cure for Typhoid and Malaria (fevers), Blood Purification, Circulation and Enhancement. Neem leaves tea is just excellent.

Beautiful & Glowing Skin: Regular use of the paste of need leaves helps the skin. Adding turmeric gives better results and adding cucumbers makes it better. Applying on the face when going to sleep works wonders. The mixture of leaves, turmeric and cucumber can also be used for skin whitening.

Chronic Wounds & Ulcers: A paste of neem leaves and turmeric are effective for Skin infections/ Rashes/ Skin Dryness. Mash or pound neem leaves and apply green juice on skin. Also use smashed leaves as a skin scrub. Diluting a little neem seed oil in water and bathing with also works against skin infections/diseases.

Skin Toner: Boil about 20 to 25 leaves in 1 liter of water in a closed vessel over a gentle flame for about 20 minutes. Then filter and put in a clean bottle and always use with the aid of a cotton to clean face with every night before going to bed. It removes dead skin, treats acne and rejuvenates skin.

Cholesterol: Neem Leaves tea lowers cholesterol

Improved Eye Health: Wash eyes with cold tea of leaves

Muscles and Joint Pains: Tea from leaves and flowers jointly boiled is a good detoxifier and anti-inflammatory

Breast, Prostate and all Cancers: Neem leaves detoxify the system, improve immune response, eliminate free radicals and inhibit inflammatory reactions. It destroys cancer cells more especially prostate cancers growth and inhibits spread

Blood Cleanser: Neem leaves tea cleanses the blood and is more effective when taken with honey

Sore Throat: Gaggle neem leaves tea several times a day

Dandruff & Hair Fall: Wash hair regularly with neem leaves tea

Painkiller: Extract of leaves and seeds together give a good anti-inflammatory effect which relieves pains, heals cuts, wounds, headaches, sprains and ear aches

Antibiotics: Leaves, barks, and almost all parts of neem have antibiotic effects, BUT the TWIGS have highest antibiotics effect

Works against dangerous bacteria like S mutans, S aureus and E Faecalis

Hair Treatment: Boil a handful of neem leaves in a little water and use to wash your hair after shampooing. It’s antifungal, antiparasitic, antibacterial and antiviral properties will help to heal your scalp of dandruff, hair fall problems and from lots of diseases

Injuries & Burns: Neem leaves juice or tea applied on them works faster. Neem leaves/bark teas prevent mouth diseases like cavities, tooth decay and gingivitis

Neem Seed Oil: Used as a mouth wash heals gum diseases. It inhibits the growth of streptococcus mutants in the mouth, a bacteria that causes oral problems

* Neem bark is effective in the treatment of gastritis and ulcers

Chicken Pox:

Drink regularly neem leaves tea and also take regular baths with it

Delays Signs of Skin Ageing: Neem oils and leaves rejuvenate skin, fights against underneath pathogens, thus keeping the skin supple and young for a long time. Add neem leaves powder to your face packs. Also dilute seed oil and use on face and body

Psoriasis: Neem oil works miraculously on psoriasis. Neem oil helps to get rid of the itches and irritation. It moisturizes skin and works against dryness and itching

Blackheads: Applying diluted Neem seed oil regularly prevents the reoccurrence of blackheads

Liver Health: Neem flowers (edible ones) detoxify, heal and protect the liver against cancers and many diseases

Leprosy:: Need seed oil when taken in appropriate amounts works against Leprosy. NB: Neem oil may be toxic when taken in large amounts into the system

Nail Diseases: Neem seed oil cures more than sixty types of nail fungus

Under-Eye Dark Circles/Bags: Mix powder from leaves with little water and apply paste with care under eyes. Only wash after 15 to 30 minutes period

Baldness: Regular application of Mashed leaves on scalp, massaging and allowing for about 30 minutes before washing, will trigger the growth of hair on bald head. Always add a little water on mashed leaves

Weak Legs: Dip legs in neem leaves solution or tea for about 30 minutes. Repeat regularly

Viral Infections: Herpes, HIV, Hepatitis, Influenza, Common Colds, Chicken Pox etc. Take neem leaves tea regular to treat symptoms, detoxify system, build immunity and possibly eradicate the disease

Tooth Ache & Teeth Treatment: Neem twigs relieve toothache and also brighten teeth when used as a chewing stick to brush teeth

Asthma: Neem oil in small dozes works against Asthma

Scars & Pigmentations: Neem is effective in lightening scars and pigmentations caused by acne and rashes or scabies. Use as prescribed above under skin problems

Poisonous Bites/Stings: Apply neem leaves juice or seed oil

Piles/Hemorrhoids: Take neem leaves tea regularly

With all these health and beauty benefits, please plant this TREE OF LIFE around your compound.


Tourism Observer

19 comments:

Linda Harry said...

HOW I GOT CURED OF HERPES VIRUS.

Hello everyone out there, i am here to give my testimony about a herbalist called dr imoloa. i was infected with herpes simplex virus 2 in 2013, i went to many hospitals for cure but there was no solution, so i was thinking on how i can get a solution out so that my body can be okay. one day i was in the pool side browsing and thinking of where i can get a solution. i go through many website were i saw so many testimonies about dr imoloa on how he cured them. i did not believe but i decided to give him a try, i contacted him and he prepared the herpes for me which i recieved through DHL courier service. i took it for two weeks after then he instructed me to go for check up, after the test i was confirmed herpes negative. am so free and happy. so, if you have problem or you are infected with any disease kindly contact him on email--- drimolaherbalmademedicine@gmail.com. or / whatssapp --+2347081986098.
This testimony serve as an expression of my gratitude. he also have herbal cure for COLD SORE, SHINGLES, CANCER, HEPATITICS A, B. DIABETES 1/2, HIV/AIDS, CHRONIC PANCERATIC, CHLAMYDIA, ZIKA VIRUS, EMPHYSEMA, LOW SPERM COUNT, ENZYMA, COUGH, ULCER, ARTHRITIS, LEUKEMIA, LYME DISEASE, ASTHMA, IMPOTENCE, BARENESS/INFERTILITY, WEAK ERECTION, PENIS ENLARGEMENT. AND SO ON.

Absar Irfan said...

Thanks a lot for writing a article on Neem tree miracle. I hate chemicals and could not find a pure Neem product for the protection of my gardening plants. At last I bought a vine of Neem Oil from Amazon in Pakistan which ensures the highest quality end-product. After the use of it my plants remain healthy from seed to harvest. I am a very happy!!!

Muddasir said...

shoplink.pk is the leading online shopping store in pakistan. Providing the best electronic, gernel , home , grocery , mobile , earphone , airpods items.

Unknown said...

I’m here to testify about what DR. ISIBOR did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 3 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Rose Smith on the internet testifying about a Man called DR. ISIBOR on how he cured her from 7 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, DR. ISIBOR prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as DR. ISIBOR assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HIV, ALS, CANCER etc. you can contact DR. ISIBOR for help via email} drisiborspellhome@gmail.com or call +2348107855231

maria said...


Good day everyone, I'm Nancy Donald , If getting herpes cure was that easy then why do a lot of people still suffer from herpes?. i was diagnosed of herpes back in 2015 and i was also told it has no cure, i have been leaving with it since then, but i kept praying and doing everything possible to get cured, so i never stopped doing research about finding a cure, i came across testimonies about people getting cured through herbal medication, and i have always believe in herbs and its medical properties, after doing so many research about it i found Dr. Obor and i discovered he was a professional in herbal medication and he has also helped many people, , we talked on phone and i confirmed he was genuine, i did all what he told me to do, i received the medicine, used it as he has prescribed, and glory be to God almighty i am completely cured, i went back to my doctor to confirm it. Do not be deceived THERE IS A CURE FOR HERPES, doctors might tell you there is no cure but WITH HERBAL MEDICATION THERE IS A CURE and if you need it contact him today on: omiawaleherbalhome@gmail.com
you can also add him on whatsapp with this number +2348105813057 or message him on his page on facebook;https://www.facebook.com/hivcurecenter/?modal=admin_todo_tour

Dominick said...

People always think if they take any external vitamins or antioxidants then their body will absorb it. But they are totally wrong. Without liposomal antioxidants, your body won't be able to absorb the perfect level of vitamins and antioxidants as it will digest with your digestive system. And to get this you can go livlong. This is the best place for all kinds of high-quality antioxidants.

John Dave said...

The doctors said Herpes virus do not have medical cure because the virus is capable of hiding within the human cells, it remains protected from your immune system. Herpes isn’t a special virus – your immune system has the tools to fight it back. But because it is able to lay dormant in protected cells, your immune system is unable to remove it from your body,But with strong reactive herbal medication is capable of getting rid of the virus gradually and totally from your body without damaging any of your cells,natural herbs kills the virus totally not just reducing the out break. Get natural herbs cure from Dr. Agbomina or reach him through his email: dragbonherbalmedicine@gmail.com or whatsapp no: +2349039139161....

Morgan Plantar said...

i am very much happy to share to every viewers that is reading this,i want to inform the whole public of how I got help for my herpes, I wanted this since 1 months ago, i have also taken treatment from some doctor, few weeks back i came on the net to see if i will be able to get any information as to cure my herpes, on my search i saw various testimony of people who was helped by a great man called Dr AGBOMINA and without any hesitation, i contact email: dragbonherbalmedicine@gmail.com , i wrote him and and he guided me, i asked him for solutions and he started the remedies for me and indeed 2 weeks after i started using the medicine, i was completely happy as it worked for me. You can contact him now for your medicine to cure your diseases, contact his Email; dragbonherbalmedicine@gmail.com , Call/Whatsapp +2349039139161..

Marie Planta said...

Greatest thanks to Dr Oyagu for his herbal drugs that he prepared for me and when i start using it in just 2weeks i was completely cured and that ended my HERPES SIMPLEX 1&2 DISEASE i am so happy and grateful to Dr Oyagu . after reading about him on a testimony of Jason Cash on a blogger. i knew suddenly Dr Oyagu was the right Doctor to cure my HERPES SIMPLEX 1&2 DISEASE. i discuss with Dr Oyagu and he prepared a herbal medicine for me and when it got sent to me in south korean . i used the herbal medicine and 2weeks and i went to check up again. after 15years of suffering from HERPES SIMPLEX 1&2 at last i am smiling once again. Dr Oyagu also has remedy to others disease like COLD SORES,HIV/AIDS,DIABETES.CANCER,HIGH BLOOD PRESSURE AND MANY MORE. I oblige everyone to contact this powerful herbalist Dr Oyagu and be free from your suffering. contact his WhatsApp line: +2348101755322 or his Email:Oyaguherbalhome@gmail.com

MARY MARSHAL said...

I am here to explore blogs forum about the wonderful and most safe cure for HERPES SIMPLEX VIRUS . I was positive to the deadly Virus called HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw Dr EDES testimony online on how he was cured so many persons from Herpes Disease. so i decided to contact the great herbalist because i know that nature has the power to heal everything. i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via FEDEX or DHL and it got to me after 4 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! its really like a dream but i'm so happy! that's the reason i decided to also add more comment of Him so that more people can be saved just like me! and if you need his help,contact his Email: (dredeshome@gmail.com) you can contact him on whatsapp +2348151937428 BLOG https://dredesherbal.webs.com
He also cure the below listed sickness;
(1) HERPES,
(2) DIABETES,
(3) HIV&AIDS,
(4) URINARY TRACT INFECTION,
(5) HEPATITIS B,
(6) IMPOTENCE,
(7) BARENESS/INFERTILITY
(8) DIARRHEA
(9) ASTHMA...

precious pound said...

Good day every one i want to inform the public on how i get cured of Herpes by a Doctor called Apala . i visited different hospital but they gave me list of expensive drugs to treat the symptoms and never cured me. A closed friend of mine introduce me to a Herbal Doctor who cured her. I was scared to contact him but i faund people testimony online testifying about his goodness. when i contacted him i asked him series of questions, i also ask him to show me his herbal certificate and license given to him by his Government he gave all the information i needed that gave me hope. He send a Herbal medicine to me that i took and it seriously worked for me. am now Herpes negative. God bless you for being a sincere and great men. Am so excited, you can contact him if you have any problem whats-app +2348114047176
.or contact him on email(dr.apalaherbalhome@gmail.com)
And he can also cure the following diseases
1) HERPES
2) HPV
4) HEPATITIS
5) ALS
6) BLOOD CANCER

Dana Lynn said...

Good day. I'm Mrs Lynn and I want to quickly share something with you. As of January 2019, I was having issues with my health and I was forced to go to the hospital. Only to be diagnosed of cancer. And as if that wasn't bad enough, it was prostate cancer. I felt like my greatest fear has finally caught up with me. I lived life like I wasn't existing no more. I was depressed, frustrated and most a times I contemplated suicide. Then one day while going through the internet checking for ways to get cured because I was getting sick of the too many drugs I was taking I stumbled across a post about a doctor called DR.Ehiaguna. I quickly messaged him because I was really desperate. I got a reply from DR.Ehiaguna and he told me what to do. And I did exactly as I was told and under two week I noticed changes. I could do things I normally found to be difficult and today I am cancer free and I will be forever grateful to doctor DR.Ehiaguna because he saved my life. Are you a cancer patient? Do you want to live a cancer free life? Then leave doctor Ehiaguna a message drehiaguna@gmail.com also WhatsApp him +2348073908953 and you'll be glad you did And He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV,Infections,ulcer  ETC

willian vivian said...

Good Day everyone, just want to share my experience here so you all should be more careful when contacting any herbalist for solution cos majority of the testimonies are fake and were the ones that fooled me.they all uses the same local code number (+234) cos i have been screwed by some of them.My Husband was suffering from Hsv for years and i went everywhere to get useful information that will help cure or suppress the disease.then i came across testimonies of those that took my hard earn money without any useful information or cure but they keep telling stories.about two months ago, a new staff was employed in my place of work and when He heard about my Husband Disease He was so remorseful and told me about Dr Emmanuel.but i felt it was still one of those Internet guys so i didn't call or text Dr Emmanuel. later that week, He asked me if i`ve heard from Dr Emmanuel and he gave me proof and reasons to try.well, lots of thanks to Dr Emmanuel cos as im writing this message, my Husband is CURED through the herbs that Dr Emmanuel sent to us.so after my experience, i decided to save some people from falling to the hands of SCAMS.thx for your time and if you require the service of Dr Emmanuel, you have to reach him via email: nativehealthclinic@gmail.com  or WhatsApp/Call +2348140073965
you can also reach me on  +1(862) 260-4433  
he have cure to all kinds of virus and disease,thank you Herpes,Hpv,Wart,Cancer,Hepatitis B,COPD,Brain Tumor Etc

patrice said...

BEST NATURAL TREATMENT FOR ITCHY SHINGLES earning that you have ITCHY SHINGLES can be one of the most difficult experiences you go through in life. You may feel scared, sad or even angry – this is OK, and a completely natural part of coping with something that can be life changing.
It will probably take a while for the news to sink in.

My name is Patrice Davis  and i am from the United States.

I remember spending so much money buying drugs from hospitals hoping that i will be cured from ITCHY SHINGLES, but all to no avail. I contacted so many  doctors and they prescribe medicine for me which they indeed tried their best but was unable to provide for me a possible cure, luckily i saw a comment about a herbal doctor, (Dr. Idedia) online.

I then contacted him (Dr. Idedia) through his email, After much chat and enquiry with the doctor, i decide to take a leap of faith because i have nothing to loose.

To my greatest surprise, Dr. Idedia prepare a medicine and  send me a Herbal Medicine through FEDEX courier Service, and he gave me guidelines on how am to take it. I followed all procedures as instructed, and after 2 weeks of taking it i was free from ITCHY SHINGLES  his medicine is legit and it is real.

I just want to encourage all individuals out there living with ITCHY SHINGLES , Genital Herpes, HSV1&2, HIV/AIDS/ HPV, COPD, CANCER, Hepatitis b, Lupus, PCOS, Kindney failure, Lung cancer and alot more. That there is still a huge chance that you can get cure only with the help of dr idedia. kindly contact him via email: dr.idediatraditionalhealinghome@gmail.com or whatsapp +2349074505296. 

Unknown said...


It’s obvious patient with HIV/AIDS OR some CANCER are been enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the virus and not a cure. I have been with the virus for 8 yrs when i was introduced by a blogger who also narrated Her story online on how she was cured of Hepatitis B after using Dr Oyakhire
Herbal Medicine. I took the same step to also get cure of HIV/AIDS, I made an order for DR Oyakhire Herbal Medicine and after taken for 2 weeks with a test result i was confirmed HIV FREE I have promise to keep telling good about this. You can Write him via his call/ whats-app him on +2349039208180 or email droyakhire7@gmail.com

Antonio Jefferson said...

Do you believe that Herpes has a permanent cure? My name is Antonio Jefferson Cole, I'm in Salt Lake City, Utah. I have been spending lots of money weekly on buying the popular Valtrex and sometimes Acyclovir, to suppress my Herpes outbreaks as prescribed to me in the hospital. Anyone who has herpes can attest this, with all the pains and embarrassing symptoms. Unfortunately, I have found out that those hospital recommended products are frequently not effective at taking care of the problem but rather make you spend all your money. DR.WATER herbal remedy will get to the root of the cause and cure you completely rather than suppress outbreaks with medication. And you will be happier, healthier, and outbreak free. He also has herbal remedies that can cure HIV, HPV, hepatitis and so on. He is the greatest of all herbal healers. His email is DRWATERHIVCURECENTRE@GMAIL.COM and his Whatsapp number: +2349050205019. You can contact him and get a permanent cure to your genital and oral Herpes or HIV AIDS or Lungs cancer or Alzheimer's disease.

Cyprienne Gueu said...

My name is Cyprienne Gueu, i was diagnosed with HIV in 2015, and since then my life was turned upside down. I even infected my husband with the virus, until i read a testimony from a woman about a healer who uses herbs to cure diseases like HIV, genital warts, herpes, Hepatitis, breast cancer , many more. And she dropped his email, which i used to contact him and told him about my problem, he assured me that he can heal me and told me all i need to do, after which he sent some herbal medicine to me in Montreal, where i was residing with my husband in Canada. He told i and my husband to take the medication for 3weeks which we did religiously. Now we are fully healed, we are now HIV negative. Even last week we went for a test again and it was all negative, thanks to the healer Dr'Water for saving our life. And i will advice any of you who needed help about this deadly virus or you want to boost your immune system against COVID-19, contact Dr'Water through his email: DRWATERHIVCURECENTRE@GMAIL.COM or Whatsapp: +2349050205019
He can also cure Cancer, Hepatitis, Herpes, HPV, Coronary artery diseases or any Illness. i believe he can help you too, thank you. If you still want to ask me anything, email me Cypriennegueu81@gmail.com

Marie Planta said...

Greatest thanks to Dr Oyagu for his herbal drugs that he prepared for me and when i start using it in just 2weeks i was completely cured and that ended my HERPES SIMPLEX 1&2 DISEASE i am so happy and grateful to Dr Oyagu . after reading about him on a testimony of Jason Cash on a blogger. i knew suddenly Dr Oyagu was the right Doctor to cure my HERPES SIMPLEX 1&2 DISEASE. i discuss with Dr Oyagu and he prepared a herbal medicine for me and when it got sent to me in south korean . i used the herbal medicine and 2weeks and i went to check up again. after 15years of suffering from HERPES SIMPLEX 1&2 at last i am smiling once again. Dr Oyagu also has remedy to others disease like COLD SORES,HIV/AIDS,DIABETES.CANCER,HIGH BLOOD PRESSURE AND MANY MORE. I oblige everyone to contact this powerful herbalist Dr Oyagu and be free from your suffering. contact his WhatsApp line: +2348101755322 or his Email:Oyaguherbalhome@gmail.com

mary robert said...

I have been suffering from Herpes for the past 3 years and 8 months, and ever since then i have been taking series of treatment but there was no improvement until i came across testimonies of Dr Ogedegbe on how he has been curing different people from different diseases all over the world, then i contacted him as well. After our conversation he sent me the medicine which i took according to his instructions. When i was done taking the herbal medicine i went for a medical checkup and to my greatest surprise i was cured from Herpes. My heart is so filled with joy. If you are suffering from Herpes or any other disease you can contact Dr Ogedegbe today on this Email address: dr.ogedegbe6@gmail.com or WhatsApp him on this Number +2348109374702  .... he also has the cure for the following..............
HPV......ALS....COPD......HIV/AIDS.....HEPATITIS A,B,C.........